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A cold-inducible RNA-binding protein (CIRP)-derived peptide attenuates inflammation and organ injury in septic mice

Cold-inducible RNA-binding protein (CIRP) is a novel sepsis inflammatory mediator and C23 is a putative CIRP competitive inhibitor. Therefore, we hypothesized that C23 can ameliorate sepsis-associated injury to the lungs and kidneys. First, we confirmed that C23 dose-dependently inhibited TNF-α rele...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Fangming, Brenner, Max, Yang, Weng-Lang, Wang, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809586/
https://ncbi.nlm.nih.gov/pubmed/29434211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13139-z
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