Blocking Cold-Inducible RNA-Binding Protein (CIRP) Protects Liver from Ischemia/Reperfusion Injury

Cold inducible RNA-binding protein (CIRP) is a nuclear protein which has been recently identified as a novel inflammatory mediator in hemorrhagic shock and sepsis. We hypothesized that CIRP acts as a potent inflammatory mediator in hepatic ischemia-reperfusion (I/R), and thus blocking CIRP protects...

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Udgivet i:Shock
Main Authors: Godwin, Andrew, Yang, Weng-Lang, Sharma, Archna, Khader, Adam, Wang, Zhimin, Zhang, Fangming, Nicastro, Jeffrey, Coppa, Gene F., Wang, Ping
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270919/
https://ncbi.nlm.nih.gov/pubmed/25186836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000251
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