CIRP-derived Peptide C23 Attenuates Inflammation and Tissue Injury in a Murine Model of Intestinal Ischemia-Reperfusion

BACKGROUND: Cold-inducible RNA-binding protein (CIRP) is a novel damage-associated molecular pattern (DAMP) that causes inflammation. C23, a short peptide derived from CIRP, has demonstrated efficacy in blocking CIRP’s activity. We hypothesize that C23 reduces inflammation and tissue injury induced...

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Publicado en:Surgery
Main Authors: McGinn, Joseph T., Aziz, Monowar, Zhang, Fangming, Yang, Weng-Lang, Nicastro, Jeffrey M., Coppa, Gene F., Wang, Ping
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261788/
https://ncbi.nlm.nih.gov/pubmed/30154017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2018.06.048
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