WNT AGONIST DECREASES TISSUE DAMAGE AND IMPROVES RENAL FUNCTION AFTER ISCHEMIA-REPERFUSION

Renal ischemia-reperfusion (IR) injury (IRI) following shock states or transplantation causes tissue damage and delayed graft function, respectively. The Wnt/β-catenin signaling pathway plays a critical role in nephrogenesis. We therefore hypothesized that pharmacological activation of Wnt/β-catenin...

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Udgivet i:Shock
Main Authors: Kuncewitch, Michael, Yang, Weng-Lang, Corbo, Lana, Khader, Adam, Nicastro, Jeffrey, Coppa, Gene F., Wang, Ping
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425639/
https://ncbi.nlm.nih.gov/pubmed/25514428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000293
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