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Stimulation of Carnitine Palmitoyltransferase 1 Improves Renal Function and Attenuates Tissue Damage after Ischemia/Reperfusion

BACKGROUND: Renal injury as a result of ischemia/reperfusion (I/R) is a major clinical problem with a high mortality rate and a lack of therapeutic treatment. During I/R, cellular homeostasis is disrupted due to energy depletion, leading to cell death. Fatty acid β-oxidation is the major metabolic p...

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Hlavní autoři: Idrovo, Juan-Pablo, Yang, Weng-Lang, Nicastro, Jeffrey, Coppa, Gene F., Wang, Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423512/
https://ncbi.nlm.nih.gov/pubmed/22698429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2012.05.053
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