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Cold-inducible RNA-binding protein (CIRP) causes sepsis-associated acute lung injury via induction of endoplasmic reticulum stress

Cold-inducible RNA-binding protein (CIRP), released into the circulation during sepsis, causes lung injury via an as yet unknown mechanism. Since endoplasmic reticulum (ER) stress is associated with acute lung injury (ALI), we hypothesized that CIRP causes ALI via induction of ER stress. To test thi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Khan, Mohammad Moshahid, Yang, Weng-Lang, Brenner, Max, Bolognese, Alexandra Cerutti, Wang, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5269663/
https://ncbi.nlm.nih.gov/pubmed/28128330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41363
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