Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis

Excessive production of proinflammatory mediators is observed in patients undergoing hemorrhagic and septic shock. Here, we report the detection of cold-inducible RNA-binding protein (CIRP) in the blood of surgical ICU individuals. In animal models of hemorrhage and sepsis, CIRP is up-regulated in s...

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Detalhes bibliográficos
Main Authors: Qiang, Xiaoling, Yang, Weng-Lang, Wu, Rongqian, Zhou, Mian, Jacob, Asha, Dong, Weifeng, Kuncewitch, Michael, Ji, Youxin, Yang, Huan, Wang, Haichao, Fujita, Jun, Nicastro, Jeffrey, Coppa, Gene F., Tracey, Kevin J., Wang, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826915/
https://ncbi.nlm.nih.gov/pubmed/24097189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3368
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