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FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor (GIST)

The cellular context that integrates upstream signaling and downstream nuclear response dictates the oncogenic behaviour and shapes treatment responses in distinct cancer types. Here, we uncover that in GIST, the forkhead family member, FOXF1, directly controls the transcription of two master regula...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Discov
Hauptverfasser: Ran, Leili, Chen, Yuedan, Sher, Jessica, Wong, Wai Pung E., Murphy, Devan, Zhang, Jenny Q., Li, Dan, Deniz, Kemal, Sirota, Inna, Cao, Zhen, Wang, Shangqian, Guan, Youxin, Shukla, Shipra, Li, Katie Yang, Chramiec, Alan, Xie, Yuanyuan, Zheng, Deyou, Koche, Richard P., Antonescu, Cristina R., Chen, Yu, Chi, Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809271/
https://ncbi.nlm.nih.gov/pubmed/29162563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-0468
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