Doses, durations, and gender predict vancomycin-induced kidney injury in pre-clinical studies

BACKGROUND: While vancomycin’s exposure-dependent efficacy thresholds have been probed, less is known regarding acute kidney injury (AKI) thresholds for vancomycin. Sensitive urinary biomarkers such as Kidney injury molecule 1 (KIM-1) have shown high sensitivity and specificity for vancomycin-associ...

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Detalhes bibliográficos
Publicado no:Int J Antimicrob Agents
Main Authors: O’Donnell, J. Nicholas, Rhodes, Nathaniel J., Miglis, Cristina M., Catovic, Lejla, Liu, Jiajun, Cluff, Cameron, Pais, Gwen, Avedissian, Sean, Joshi, Medha, Griffin, Brooke, Prozialeck, Walter, Gulati, Anil, Lodise, Thomas P., Scheetz, Marc H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807205/
https://ncbi.nlm.nih.gov/pubmed/28803934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2017.08.012
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