1419. 24-Hour Pharmacokinetic Relationships for Intravenous Vancomycin and Novel Urinary Biomarkers of Acute Kidney Injury

BACKGROUND: Vancomycin induces exposure-related acute kidney injury; yet only troughs are generally monitored in patients. In rat models, intraperitoneal dosing results in highly variable drug exposures. Thus, intravenous (IV) vancomycin was used to assess pharmacokinetic-toxicodynamic (PK-TD) relat...

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Publicado no:Open Forum Infect Dis
Main Authors: Avedissian, Sean, Liu, Jiajun, O’Donnell, J Nicholas, Pais, Gwendolyn, Becher, Leighton, Joshi, Medha, Prozialeck, Walter, Lamar, Peter, Lodise, Thomas P, Scheetz, Marc H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254309/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1250
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