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N(6)-Formyllysine as a biomarker of formaldehyde exposure: Formation and loss of N(6)-formyllysine in nasal epithelium in long-term, low-dose inhalation studies in rats

Exposure to both endogenous and exogenous formaldehyde has been established to be carcinogenic, likely by virtue of forming nucleic acid and proteins adducts such as N(6)-formyllysine. To better assess N(6)-formyllysine as a biomarker of formaldehyde exposure, we studied accumulation of N(6)-formyll...

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Bibliographic Details
Published in:Chem Res Toxicol
Main Authors: Edrissi, Bahar, Taghizadeh, Koli, Moeller, Benjamin C., Yu, Rui, Kracko, Dean, Doyle-Eisele, Melanie, Swenberg, James A., Dedon, Peter C.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807069/
https://ncbi.nlm.nih.gov/pubmed/28692800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.7b00075
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