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Molecular Dosimetry of N(2)-hydroxymethyl-dG DNA Adducts in Rats Exposed to Formaldehyde
In this study, both endogenous and exogenous N(2)-hydroxymethyl-dG adducts in nasal DNA of rats exposed to 0.7, 2, 5.8, 9.1 or 15.2 ppm [(13)CD(2)] formaldehyde for 6 h were quantified by a highly sensitive nano-UPLC-MS/MS method. Our data clearly demonstrated that exogenous formaldehyde DNA adducts...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128468/ https://ncbi.nlm.nih.gov/pubmed/21155545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx1003886 |
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