Molecular Dosimetry of Endogenous and Exogenous O(6)-Methyl-dG and N7-Methyl-G Adducts Following Low Dose [D(3)]-Methylnitrosourea Exposures in Cultured Human Cells

[Image: see text] For DNA-reactive chemicals, a low dose linear assessment of cancer risk is the science policy default. In the present study, we quantitated the endogenous and exogenous N7-methyl-G and O(6)-methyl-dG adducts in human lymphoblastoid cells exposed to low dose [D(3)]-methylnitrosourea...

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Xehetasun bibliografikoak
Egile Nagusiak: Sharma, Vyom, Collins, Leonard B., Clement, Jean M., Zhang, Zhenfa, Nakamura, Jun, Swenberg, James A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2014
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998766/
https://ncbi.nlm.nih.gov/pubmed/24628573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx5000602
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