Evidence that endogenous formaldehyde produces immunogenic and atherogenic adduct epitopes

Endogenous formaldehyde is abundantly present in our bodies, at around 100 µM under normal conditions. While such high steady state levels of formaldehyde may be derived by enzymatic reactions including oxidative demethylation/deamination and myeloperoxidation, it is unclear whether endogenous forma...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakamura, Jun, Shimomoto, Takasumi, Collins, Leonard B., Holley, Darcy W., Zhang, Zhenfa, Barbee, Jenna M., Sharma, Vyom, Tian, Xu, Kondo, Tomohiro, Uchida, Koji, Yi, Xianwen, Perkins, Diana O., Willis, Monte S., Gold, Avram, Bultman, Scott J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589919/
https://ncbi.nlm.nih.gov/pubmed/28883613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11289-8
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