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The Effect of Formaldehyde Fixation on RNA: Optimization of Formaldehyde Adduct Removal
Formalin-fixed, paraffin-embedded tissues generally provide low yields of extractable RNA that exhibit both covalent modification of nucleic acid bases and strand cleavage. This frustrates efforts to perform retrospective analyses of gene expression using archival tissue specimens. A variety of cond...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Investigative Pathology
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077733/ https://ncbi.nlm.nih.gov/pubmed/21497290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2011.01.010 |
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