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Use of LC-MS/MS and Stable Isotopes to Differentiate Hydroxymethyl and Methyl DNA Adducts from Formaldehyde and Nitrosodimethylamine

Formaldehyde is a known human and animal carcinogen that forms DNA adducts, and causes mutations. While there is widespread exposure to formaldehyde in the environment, formaldehyde is also an essential biochemical in all living cells. The presence of both endogenous and exogenous sources of formald...

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Dettagli Bibliografici
Autori principali: Lu, Kun, Craft, Sessaly, Nakamura, Jun, Moeller, Benjamin C., Swenberg, James A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307879/
https://ncbi.nlm.nih.gov/pubmed/22148432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200426b
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