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Determination of N(2)-hydroxymethyl-dG Adducts in Nasal Epithelium and Bone Marrow of Non-human Primates following (13)CD(2)-Formaldehyde Inhalation Exposure

The presence of endogenous and exogenous N(2)-hydroxymethyl-dG adducts in DNA from nasal mucosa and bone marrow of cynomolgus macaques exposed to 1.9 and 6.1 ppm of [(13)CD(2)]-formaldehyde for 6 hours a day for 2 consecutive days was investigated using a highly sensitive nano-UPLC-MS/MS method with...

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Bibliographische Detailangaben
Hauptverfasser: Moeller, Benjamin C., Lu, Kun, Doyle-Eisele, Melanie, McDonald, Jacob, Gigliotti, Andrew, Swenberg, James A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273041/
https://ncbi.nlm.nih.gov/pubmed/21222454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx1004166
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