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Intramolecular diffusion controls aggregation of the PAPf39 peptide

The 39-residue fragment of human prostatic acidic phosphatase (PAP) is found in high concentrations in semen and easily form fibrils. Previous work has shown that fibrillization is accelerated with a deletion of the first 8, mostly charged residues and it was hypothesized that fibrillization depende...

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Detalles Bibliográficos
Publicado en:Biophys Chem
Autores principales: Srivastava, Kinshuk R., French, Kinsley C., Tzul, Franco O., Makhatadze, George I., Lapidus, Lisa J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806150/
https://ncbi.nlm.nih.gov/pubmed/27393931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2016.06.004
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