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CORE SEQUENCE OF PAPF39 AMYLOID FIBRILS AND THE MECHANISM OF pH DEPENDENT FIBRIL FORMATION: THE ROLE OF MONOMER CONFORMATION

PAPf39, a 39 residue peptide fragment from human prostatic acidic phosphatase, has been shown to form amyloid fibrils in semen (SEVI), which increase HIV infectivity by up to five orders of magnitude. The sequence of the PAPf39 fibrillar core was identified using HDXMS and protease protection assays...

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Bibliografische gegevens
Hoofdauteurs: French, Kinsley C., Makhatadze, George I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549435/
https://ncbi.nlm.nih.gov/pubmed/23215256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301406d
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