Selective Radical Trifluoromethylation of Native Residues in Proteins

[Image: see text] The incorporation of fluorine can not only significantly facilitate the study of proteins but also potentially modulate their function. Though some biosynthetic methods allow global residue-replacement, post-translational fluorine incorporation would constitute a fast and efficient...

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Pubblicato in:J Am Chem Soc
Autori principali: Imiołek, Mateusz, Karunanithy, Gogulan, Ng, Wai-Lung, Baldwin, Andrew J., Gouverneur, Véronique, Davis, Benjamin G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2018
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806083/
https://ncbi.nlm.nih.gov/pubmed/29301396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b10230
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