Reactivation of androgen receptor-regulated lipid biosynthesis drives the progression of castration-resistant prostate cancer

Androgen receptor (AR) is a transcriptional activator that, in prostate cells, stimulates gene expression required for various cellular functions, including metabolisms and proliferation. AR signaling is also essential for the development of hormone-dependent prostate cancer (PCa) and its activity c...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Han, W, Gao, S, Barrett, D, Ahmed, M, Han, D, Macoska, J A, He, H H, Cai, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805650/
https://ncbi.nlm.nih.gov/pubmed/29059155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.385
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