Nalaganje...
ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer
The androgen receptor (AR) is overexpressed and hyperactivated in human castration-resistant prostate cancer (CRPC). However, the determinants of AR overexpression in CRPC are poorly defined. Here we show that retinoid acid receptor-related orphan receptor γ (ROR-γ) is overexpressed and amplified in...
Shranjeno v:
| izdano v: | Nat Med |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5030109/ https://ncbi.nlm.nih.gov/pubmed/27019329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4070 |
| Oznake: |
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