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Aberrant activation of androgen receptor in a new neuropeptide-autocrine model of androgen-insensitive prostate cancer

Treatments of advanced prostate cancer with androgen deprivation therapy inevitably render the tumors to become castration resistant and incurable. Under these conditions, neuroendocrine differentiation of prostate cancer (CaP) cells is often detected and neuropeptides released by these cells may fa...

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Autori principali: Yang, Joy C., Ok, Joon-ha, Busby, J. Erik, Borowsky, Alexander D., Kung, Hsing-Jien, Evans, Christopher P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626435/
https://ncbi.nlm.nih.gov/pubmed/19117998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0442
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