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Intracellular Permeation of Na(+) in an Active State G-Protein Coupled Receptor
Playing a central role in cell signaling, GPCRs have evolved into the largest superfamily of membrane proteins and form the majority of drug targets in humans. How extracellular agonist binding triggers the activation of GPCRs and associated intracellular effector proteins remains, however, poorly u...
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| 發表在: | Structure |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5805466/ https://ncbi.nlm.nih.gov/pubmed/29249607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.11.013 |
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