Intracellular Permeation of Na(+) in an Active State G-Protein Coupled Receptor

Playing a central role in cell signaling, GPCRs have evolved into the largest superfamily of membrane proteins and form the majority of drug targets in humans. How extracellular agonist binding triggers the activation of GPCRs and associated intracellular effector proteins remains, however, poorly u...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Vickery, Owen N., Carvalheda, Catarina A., Zaidi, Saheem A., Pisliakov, Andrei V., Katritch, Vsevolod, Zachariae, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805466/
https://ncbi.nlm.nih.gov/pubmed/29249607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.11.013
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https://ncbi.nlm.nih.gov/pmc/articles/PMC5805466/
https://ncbi.nlm.nih.gov/pubmed/29249607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.11.013

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