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Multiple kinases inhibit origin licensing and helicase activation to ensure reductive cell division during meiosis

Meiotic cells undergo a single round of DNA replication followed by two rounds of chromosome segregation (the meiotic divisions) to produce haploid gametes. Both DNA replication and chromosome segregation are similarly regulated by CDK oscillations in mitotic cells. Yet how these two events are unco...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Phizicky, David V, Berchowitz, Luke E, Bell, Stephen P
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805409/
https://ncbi.nlm.nih.gov/pubmed/29388912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33309
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