Long-Lasting In Vivo Effects of the Cannabinoid CB1 Antagonist AM6538

AM6538 is a cannabinoid antagonist that binds CB1 receptors expressed in HEK-293 cells in a wash-resistant manner. The effects of AM6538 in live animals has not previously been established. We characterized the antagonist effects of AM6538 in male mice, using a warm-water tail-withdrawal assay, and...

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Detaylı Bibliyografya
Yayımlandı:J Pharmacol Exp Ther
Asıl Yazarlar: Paronis, Carol A., Chopda, Girish R., Vemuri, Kiran, Zakarian, Ani S., Makriyannis, Alexandros, Bergman, Jack
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2018
Konular:
Behavioral Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5803641/
https://ncbi.nlm.nih.gov/pubmed/29311110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.245647
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