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Parkin clearance of dysfunctional mitochondria regulates ROS levels and increases survival of human chondrocytes
OBJECTIVE: Mitochondrial dysfunction, oxidative stress and chondrocyte death are important contributors to the development and pathogenesis of osteoarthritis (OA). In this study, we determined the expression and role of Parkin in the clearance of damaged/dysfunctional mitochondria, regulation of ROS...
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| 發表在: | Osteoarthritis Cartilage |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5803469/ https://ncbi.nlm.nih.gov/pubmed/28801211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2017.07.020 |
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