Wogonin, a plant derived small molecule, exerts potent anti-inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes

Osteoarthritis (OA), characterized by progressive destruction of articular cartilage, is the most common form of human arthritis. Here, we evaluated the potential chondroprotective and anti-inflammatory effects of Wogonin, a naturally occurring flavonoid, in IL-1β-stimulated human OA chondrocytes an...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Khan, Nazir M., Haseeb, Abdul, Ansari, Mohammad Y., Devarapalli, Pratap, Haynie, Sara, Haqqi, Tariq M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490997/
https://ncbi.nlm.nih.gov/pubmed/28237856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.02.041
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