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A wogonin-rich-fraction of Scutellaria baicalensis root extract exerts chondroprotective effects by suppressing IL-1β-induced activation of AP-1 in human OA chondrocytes

Osteoarthritis (OA) is a common joint disorder with varying degrees of inflammation and sustained oxidative stress. The root extract of Scutellaria baicalensis (SBE) has been used for the treatment of inflammatory and other diseases. Here, we performed activity-guided HPLC-fractionation of SBE, iden...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Khan, Nazir M., Haseeb, Abdul, Ansari, Mohammad Y., Haqqi, Tariq M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335554/
https://ncbi.nlm.nih.gov/pubmed/28256567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43789
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