Chondroprotective effects of a proanthocyanidin rich Amazonian genonutrient reflects direct inhibition of matrix metalloproteinases and upregulation of IGF-1 production by human chondrocytes

BACKGROUND: The Amazonian medicinal plant Sangre de grado (Croton palanostigma) has traditional applications for the treatment of wound healing and inflammation. We sought to characterize two extracts (progrado and zangrado) in terms of safety and oligomeric proanthocyanidin chain length. Additional...

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Hlavní autoři: Miller, Mark JS, Bobrowski, Paul, Shukla, Meenakshi, Gupta, Kalpana, Haqqi, Tariq M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1971260/
https://ncbi.nlm.nih.gov/pubmed/17697350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-4-16
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