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Wogonin, a natural flavonoid, intercalates with genomic DNA and exhibits protective effects in IL-1β stimulated osteoarthritis chondrocytes

Wogonin has recently been shown to possess anti-inflammatory and chondroprotective properties and is of considerable interest due to its broad pharmacological activities. The present study highlights that Wogonin bind DNA and exerts chondroprotective effects in vitro. Wogonin showed strong binding w...

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Publicat a:Chem Biol Interact
Autors principals: Khan, Nazir M., Ahmad, Imran, Ansari, Mohammad Y., Haqqi, Tariq M.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548605/
https://ncbi.nlm.nih.gov/pubmed/28688942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2017.06.025
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