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Wogonin, a natural flavonoid, intercalates with genomic DNA and exhibits protective effects in IL-1β stimulated osteoarthritis chondrocytes

Wogonin has recently been shown to possess anti-inflammatory and chondroprotective properties and is of considerable interest due to its broad pharmacological activities. The present study highlights that Wogonin bind DNA and exerts chondroprotective effects in vitro. Wogonin showed strong binding w...

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Detalhes bibliográficos
Publicado no:Chem Biol Interact
Main Authors: Khan, Nazir M., Ahmad, Imran, Ansari, Mohammad Y., Haqqi, Tariq M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548605/
https://ncbi.nlm.nih.gov/pubmed/28688942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2017.06.025
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