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Hypertrophic cardiomyopathy and the myosin mesa: viewing an old disease in a new light

The sarcomere is an exquisitely designed apparatus that is capable of generating force, which in the case of the heart results in the pumping of blood throughout the body. At the molecular level, an ATP-dependent interaction of myosin with actin drives the contraction and force generation of the sar...

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Bibliografske podrobnosti
izdano v:Biophys Rev
Main Authors: Trivedi, Darshan V., Adhikari, Arjun S., Sarkar, Saswata S., Ruppel, Kathleen M., Spudich, James A.
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5803174/
https://ncbi.nlm.nih.gov/pubmed/28717924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-017-0274-6
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