Chronic morphine exposure potentiates p-glycoprotein trafficking from nuclear reservoirs in cortical rat brain microvessels

The rates of opioid prescription and use have continued to increase over the last few decades resulting in a greater number of opioid tolerant patients. Treatment of acute pain from surgery and injury is a clinical challenge for these patients. Several pain management strategies including prescribin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Schaefer, Charles P., Arkwright, Nathan B., Jacobs, Leigh M., Jarvis, Chelsea K., Hunn, Kristen C., Largent-Milnes, Tally M., Tome, Margaret E., Davis, Thomas P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802945/
https://ncbi.nlm.nih.gov/pubmed/29414996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192340
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