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Chemical and Physical Variability in Structural Isomers of an L/D α-Sheet Peptide Designed To Inhibit Amyloidogenesis
There has been much interest in synthetic peptides as inhibitors of aggregation associated with amyloid diseases. Of particular interest are compounds that target the cytotoxic soluble oligomers preceding the formation of mature, nontoxic fibrils. This study explores physical and chemical difference...
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| Veröffentlicht in: | Biochemistry |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5801053/ https://ncbi.nlm.nih.gov/pubmed/29202245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00345 |
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