The Stress Kinase JNK Regulates Gap Junction Cx43 Gene Expression and Promotes Atrial Fibrillation in the Aged Heart

BACKGROUND: The stress kinase c-jun N-terminal kinase (JNK) is critical in the pathogenesis of cardiac diseases associated with an increased incidence of atrial fibrillation (AF), the most common arrhythmia in the elderly. We recently discovered that JNK activation is linked to the loss of gap junct...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Yan, Jiajie, Thomson, Justin K, Zhao, Weiwei, Wu, Xiaomin, Gao, Xianlong, DeMarco, Dominic, Kong, Wei, Tong, Min, Sun, Jun, Bakhos, Mamdouh, Fast, Vladimir G., Liang, Qingrong, Prabhu, Sumanth D, Ai, Xun
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800987/
https://ncbi.nlm.nih.gov/pubmed/29146153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.11.006
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