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Chemokine-mediated choreography of thymocyte development and selection

As they differentiate, thymocytes encounter spatially restricted cues critical for differentiation and selection of a functional, self-tolerant T cell repertoire. Sequential migration of developing T cells through distinct thymic microenvironments is enforced by the ordered expression of chemokine r...

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Pubblicato in:Trends Immunol
Autori principali: Lancaster, Jessica N., Li, Yu, Ehrlich, Lauren I. R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800975/
https://ncbi.nlm.nih.gov/pubmed/29162323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2017.10.007
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