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Biophysical models of protein evolution: Understanding the patterns of evolutionary sequence divergence
For decades, rates of protein evolution have been interpreted in terms of the vague concept of “functional importance”. Slowly evolving proteins or sites within proteins were assumed to be more functionally important and thus subject to stronger selection pressure. More recently, biophysical models...
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| Опубликовано в: : | Annu Rev Biophys |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800964/ https://ncbi.nlm.nih.gov/pubmed/28301766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biophys-070816-033819 |
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