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Drug-drug interactions between Atorvastatin and Dronedarone mediated by monomeric CYP3A4

Heterotropic interactions between atorvastatin (ARVS) and dronedarone (DND) have been deciphered using global analysis of the results of binding and turnover experiments for pure drugs and their mixtures. The in vivo presence of atorvastatin lactone (ARVL) was explicitly taken into account by using...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochemistry
Egile Nagusiak: Denisov, Ilia G., Baylon, Javier L., Grinkova, Yelena V., Tajkhorshid, Emad, Sligar, Stephen G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800941/
https://ncbi.nlm.nih.gov/pubmed/29200287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01012
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