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RGS4 Overexpression in Lung Attenuates Airway Hyperresponsiveness in Mice
A cardinal feature of asthma is airway hyperresponsiveness (AHR) to spasmogens, many of which activate G protein–coupled receptors (GPCRs) on airway smooth muscle (ASM) cells. Asthma subtypes associated with allergy are characterized by eosinophilic inflammation in the lung due to the type 2 immune...
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| Опубликовано в: : | Am J Respir Cell Mol Biol |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Thoracic Society
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800898/ https://ncbi.nlm.nih.gov/pubmed/28853915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0109OC |
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