Formaldehyde Induces Rho-Associated Kinase Activity to Evoke Airway Hyperresponsiveness

Formaldehyde, a common indoor air pollutant, exacerbates asthma and synergizes with allergen to induce airway hyperresponsiveness (AHR) in animal models. The mechanisms mediating formaldehyde-induced AHR remain poorly understood. We posit that formaldehyde modulates agonist-induced contractile respo...

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Udgivet i:Am J Respir Cell Mol Biol
Main Authors: Jude, Joseph, Koziol-White, Cynthia, Scala, Jacqueline, Yoo, Edwin, Jester, William, Maute, Christopher, Dalton, Pamela, Panettieri, Reynold
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070102/
https://ncbi.nlm.nih.gov/pubmed/27149505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0254OC
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