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Loss of Regulator of G protein signaling 5 promotes airway hyperresponsiveness in the absence of allergic inflammation

BACKGROUND: Although eosinophilic inflammation typifies allergic asthma, it is not a prerequisite for AHR, suggesting that underlying abnormalities in structural cells such as airway smooth muscle (ASM) contribute to the asthmatic diathesis. Dysregulation of procontractile, G protein-coupled recepto...

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Detalhes bibliográficos
Main Authors: Balenga, Nariman A., Jester, William, Jiang, Meiqi, Panettieri, Reynold A., Druey, Kirk M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119844/
https://ncbi.nlm.nih.gov/pubmed/24666695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.01.019
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