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Loss of Regulator of G protein signaling 5 promotes airway hyperresponsiveness in the absence of allergic inflammation
BACKGROUND: Although eosinophilic inflammation typifies allergic asthma, it is not a prerequisite for AHR, suggesting that underlying abnormalities in structural cells such as airway smooth muscle (ASM) contribute to the asthmatic diathesis. Dysregulation of procontractile, G protein-coupled recepto...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119844/ https://ncbi.nlm.nih.gov/pubmed/24666695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.01.019 |
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