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Discovery of a Potent Dual ALK and EGFR T790M Inhibitor
The mutational activations of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR) are validated oncogenic events and the targets of approved drugs to treat non-small cell lung cancer (NSCLC). Here we report highly potent dual small molecule inhibitors of both ALK and EGFR, p...
में बचाया:
| में प्रकाशित: | Eur J Med Chem |
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| मुख्य लेखकों: | , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800871/ https://ncbi.nlm.nih.gov/pubmed/28528303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2017.04.079 |
| टैग : |
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