Загрузка...
Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors
[Image: see text] Allosteric kinase inhibitors represent a promising new therapeutic strategy for targeting kinases harboring oncogenic driver mutations in cancers. Here, we report the discovery, optimization, and structural characterization of allosteric mutant-selective EGFR inhibitors comprising...
Сохранить в:
| Опубликовано в: : | ACS Med Chem Lett |
|---|---|
| Главные авторы: | , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Chemical
Society
2019
|
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6862338/ https://ncbi.nlm.nih.gov/pubmed/31749909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00381 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|