Single and dual targeting of mutant EGFR with an allosteric inhibitor

Antzeko izenburuak

• Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors
  nork: De Clercq, Dries J. H., et al.
  Argitaratua: (2019)
• Mutant-Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug-Resistant Mutations
  nork: Jang, Jaebong, et al.
  Argitaratua: (2020)
• Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors
  nork: Tyler S. Beyett, et al.
  Argitaratua: (2022-05-01)
• Discovery of a Potent Dual ALK and EGFR T790M Inhibitor
  nork: Jang, Jaebong, et al.
  Argitaratua: (2017)
• Overcoming EGFR T790M and C797S resistance with mutant-selective allosteric inhibitors
  nork: Jia, Yong, et al.
  Argitaratua: (2016)