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L1 retrotransposon antisense RNA within ASAR lncRNAs controls chromosome-wide replication timing

Mammalian cells replicate their chromosomes via a temporal replication program. The ASAR6 and ASAR15 genes were identified as loci that when disrupted result in delayed replication and condensation of entire human chromosomes. ASAR6 and ASAR15 are monoallelically expressed long noncoding RNAs that r...

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書目詳細資料
發表在:J Cell Biol
Main Authors: Platt, Emily J., Smith, Leslie, Thayer, Mathew J.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800813/
https://ncbi.nlm.nih.gov/pubmed/29288153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201707082
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