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L1 retrotransposon antisense RNA within ASAR lncRNAs controls chromosome-wide replication timing

Mammalian cells replicate their chromosomes via a temporal replication program. The ASAR6 and ASAR15 genes were identified as loci that when disrupted result in delayed replication and condensation of entire human chromosomes. ASAR6 and ASAR15 are monoallelically expressed long noncoding RNAs that r...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Platt, Emily J., Smith, Leslie, Thayer, Mathew J.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800813/
https://ncbi.nlm.nih.gov/pubmed/29288153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201707082
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