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L1 retrotransposon antisense RNA within ASAR lncRNAs controls chromosome-wide replication timing

Mammalian cells replicate their chromosomes via a temporal replication program. The ASAR6 and ASAR15 genes were identified as loci that when disrupted result in delayed replication and condensation of entire human chromosomes. ASAR6 and ASAR15 are monoallelically expressed long noncoding RNAs that r...

詳細記述

保存先:
書誌詳細
出版年:J Cell Biol
主要な著者: Platt, Emily J., Smith, Leslie, Thayer, Mathew J.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800813/
https://ncbi.nlm.nih.gov/pubmed/29288153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201707082
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