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L1 retrotransposon antisense RNA within ASAR lncRNAs controls chromosome-wide replication timing
Mammalian cells replicate their chromosomes via a temporal replication program. The ASAR6 and ASAR15 genes were identified as loci that when disrupted result in delayed replication and condensation of entire human chromosomes. ASAR6 and ASAR15 are monoallelically expressed long noncoding RNAs that r...
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| Publié dans: | J Cell Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800813/ https://ncbi.nlm.nih.gov/pubmed/29288153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201707082 |
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